Old news - The Louisville Leader\u27s genealogical gems.

The Louisville Leader African-American community newspaper, published weekly in Louisville from 1917 to 1950, offers a perspective on local and national events not available in the mainstream media at the time. The newspaper\u27s columns highlighting community members’ life events and activities may be of great interest to social historians and genealogists

Preserving digital information.

The University of Louisville participates in a federally-funded partnership, the MetaArchive Cooperative, to develop a protocol for the distributed preservation of digital cultural heritage materials

CHARACTERIZATION OF THE TWO VACCINIA VIRUS MATURE VIRION-SPECIFIC PROTEINS, A26P AND A25P

Poxviruses produce two morphologically distinct infectious particles, mature virions (MVs) and extracellular virions (EVs). During replication, some MVs differentiate and become wrapped with cellular membranes, transported to the periphery, and exported as EVs. Some orthopoxviruses, e.g., cowpox virus (CPXV), form large, discrete cytoplasmic inclusions called A-type inclusion bodies (ATIs) within which MVs are embedded by a process called occlusion. ATIs are composed of aggregates of the A-type inclusion protein (ATIp), which is truncated in orthopoxviruses such as vaccinia virus (VACV) that fail to form ATIs. VACV does encode a functional A26p, which along with the ATIp is required for occlusion. A26 lacks a transmembrane domain, and nothing is known regarding how it associates with the MV and regulates occlusion. Additionally, little is known about the formation of ATIs and how MVs become embedded within them. Here, experiments show that A26p is incorporated into MVs by the A27p-A17p complex and interacts with A25p, a truncated form of the CPXV ATIp. Restoration of the full-length ATI gene is sufficient for VACV ATI formation and the occlusion of MVs. A26p directly interacts with ATIp, and this interaction, as well as the A26p-A27p interaction, are required for occlusion. The data demonstrates that ATI mRNAs are transported out of viral factories (VFs) and translated in the cytoplasm. ATIs enlarge both by new protein synthesis and by coalescence, which requires microtubules. ATIs do not nucleate around MVs but rather MVs move along microtubules to embed within ATIs. Taken together, the data suggest a model for occlusion in which MVs move along microtubules to ATIs that are translated from mRNAs in the cytoplasm. At the ATIs, A26p has a bridging role between ATIp and A27p, and A27p provides a link to the MV membrane. Although the specificity of A26p for MVs suggested A26p might regulate wrapping, I did not detect an effect of either the deletion of A26 or occlusion on the production of EVs

Understanding the Growth in Welfare Benefit Receipt in Britain: A Review of the Evidence

This paper summarises the conclusions from a more extensive report commissioned by the Treasury and the Ministry of Social Policy to provide an explanation of growth in welfare benefit receipt in Britain in the period 1971 to 1997. The study is structured around a simple heuristic model of four sets of influences, 'drivers', the interaction of which helps to explain trends in claimant caseloads: the economy, demography, welfare institutions and belief systems. Four sets of claimants are considered: unemployed people, disabled people, retirement pensioners and children and families. It assembles a widely dispersed literature, in the first comprehensive review of the evidence on this issue. The conclusions reported here are supported in the full report by a wide range of data and analyses. The full report has been extensively edited, updated, reformatted and published in September 2000 by the Policy Press at the University of Bristol, under the title The Making of A Welfare Class? Benefit receipt in Britain, by Robert Walker with Marilyn Howard. Details of this publication may be obtained through the link to the Policy Press website: http://www.bris.ac.uk/Publications/TPP/catalog.htm The study concludes that, while caseloads increased across the four domains, they did so for very different reasons. While the process of de-industrialisation provided an important back-cloth to all the changes, it was only directly implicated as a major influence in the growth of unemployment related benefits. The upward trends in disability benefits were principally a reflection of the greater social awareness of the personal costs of disability, while the growth in benefits pertaining to the family was very largely a response to changing social attitudes and sexual behaviour. Demography, notably increased longevity, explains the observed growth in pensioner caseloads although the balance between contributory and means-tested pensions was the result of foresighted policy decisions made between the 1940s and 1970s.

Dialogues with early medieval ‘warriors’

How are early medieval graves interpreted by community archaeology projects? This chapter considers how the well-known and innovative Operational Nightingale project has distinctively deployed the excavation and analysis of early Anglo-Saxon (later 5th and 6th-century AD) furnished graves, including those containing weaponry, in its practice and public engagement. In light of recent discussions regarding the ideological, social, educational and emotional significances of the archaeological dead, we consider Operation Nightingale’s well-received practical and interpretative dialogues with the dead during the investigation of an early medieval cemetery at Barrow Clump, Figheldean, on Salisbury Plain, Wiltshire. Our focus is upon the project’s assertions of parity and affinity between early Anglo-Saxon weapon burials and the experiences of modern military personnel: dialogues with early medieval ‘warriors’

The Effects of Community Building Music on Transition Time in an Early Childhood Montessori Classroom

The purpose of this action research study was to determine how community building music would affect the transition time in a primary Montessori classroom. The researchers were two female preschool teachers in public Montessori schools. The participants, aged three to six years old, were involved in a daily clean-up time, which took place before the study began. The teachers added a music intervention for four weeks to see if the dynamics of clean-up time would change. The teachers documented the research study using qualitative and quantitative data tools. The data tools included student surveys, teacher journals, a timer log, and a classroom tracker sheet. The intervention findings showed an overall decrease in the amount of time students took to clean up and an increase in happiness and community involvement in the classroom. Future researchers should consider the pre and post student survey be completed on an individual basis. Additionally, increase the length of baseline data collection and intervention

The University of Louisville School of Music Guest Book : from local treasure to online resource.

A collaboration between the University of Louisville’s Dwight Anderson Music Library and Digital Initiatives Department has resulted in the digitization of the University of Louisville School of Music Guest Book. Begun in 1949, the book contains signatures and handwritten messages from many of the most well-known musicians of the twentieth and twenty-first centuries. This article describes the approach to scanning, cataloging, indexing, and providing full-text searchable online access to the guest book using CONTENTdm digital media management software. It addresses resource and technical challenges encountered and overcome

Publishing Partnership: Facilitating Open Access through Libraries Collaboration with Clinical Departments

When the University of Louisville Libraries launched the ThinkIR institutional repository on the bepress Digital Commons platform in 2015, we anticipated offering open access journal publishing several years in the future. However, the Division of Infectious Diseases’ eagerness to find a venue to facilitate the equitable movement of research and information into the larger global community resulted in a partnership beginning in 2016 to publish two open access journals on the platform, which then served as a model for other health sciences journals, including one from the Emergency Medicine Department. The benefits, including the opportunity to provide free open access to research on topics that became even more relevant as a result of the COVID-19 pandemic and to increase the value of the Libraries to clinical departments, far outweighed the challenges of limited resources, learning curves, and managing expectations.This presentation will cover the importance of a memorandum of understanding between the Libraries and the health sciences departments in delineating roles and responsibilities and managing expectations; the Libraries’ tasks and consultations on author agreements, persistent identifiers, metadata, technical support, and indexing, as well as copy editing; and the challenges, goals, and impact of the journals themselves

Pathways to open access : the story of an institutional repository and how we built it.

The central purpose of an institutional repository (IR) is providing open access to scholarship. That scholarship originates primarily through the work of faculty and students at research institutions, leading research libraries to embrace IRs and the scholarly communication movement. IRs typically include student theses and dissertations and faculty publications but sometimes extend far beyond to institutional records and documents. Launching an IR requires significant collaborative work across disparate specialties and institutional structures to establish policies, workflows, configure metadata and technology for retrieval, and fashion outreach and ongoing support to the administrators and ultimately provide mediated support to the scholars who produce the scholarship. The University of Louisville recently launched ThinkIR (http://ir.library.louisville.edu) by building on a foundation of a decade’s work with theses and dissertations (ETDs) through Technical Services. UofL is now growing ThinkIR by leveraging the talents of other library faculty and staff with legal, outreach, archival, technical, and administrative skills not only to effectively manage those requirements but also to reflect the needs and skills of the seemingly disparate specialties, fostering a broader understanding of the IR within the Libraries and UofL community. IRs by history and existence embody the changing roles of academic libraries and allow scholars to broadly share and successfully manage their long term interests in their scholarship. This presentation will explore those themes and address how, led by a cross-unit Scholarly Communication and Data Management Team, we have spanned past practices, evolving best practices, and the unique needs of our campus to collaboratively build ThinkIR